Virulence factor regulator (Vfr) controls virulence-associated phenotypes inPseudomonas syringaepv.tabaci6605 by a quorum sensing-independent mechanism
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منابع مشابه
Quorum Sensing in Microbial Virulence
Cell-to cell communication occurs via a signaling pathway referred to as quorum sensing. There are four main types of these systems according to the chemical nature of signal molecules used by microorganisms to elicit expression of target genes in response to environmental stimuli or need of microbial communities. Type I system acts by using acyl homoserine lactones as signals to trigger the ex...
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Pseudomonas aeruginosa controls several genes in a cell density-dependent manner through a phenomenon termed quorum sensing. The transcriptional activator protein of the las quorum-sensing system is encoded for by the lasR gene, which is at the top of a quorum-sensing hierarchy. The activation of LasR as a transcriptional activator induces the expression of multiple genes that code for factors ...
متن کاملThe Pseudomonas aeruginosa Vfr regulator controls global virulence factor expression through cyclic AMP-dependent and -independent mechanisms.
Vfr is a global regulator of virulence factor expression in the human pathogen Pseudomonas aeruginosa. Although indirect evidence suggests that Vfr activity is controlled by cyclic AMP (cAMP), it has been hypothesized that the putative cAMP binding pocket of Vfr may accommodate additional cyclic nucleotides. In this study, we used two different approaches to generate apo-Vfr and examined its ab...
متن کاملIntrinsic Thermal Sensing Controls Proteolysis of Yersinia Virulence Regulator RovA
Pathogens, which alternate between environmental reservoirs and a mammalian host, frequently use thermal sensing devices to adjust virulence gene expression. Here, we identify the Yersinia virulence regulator RovA as a protein thermometer. Thermal shifts encountered upon host entry lead to a reversible conformational change of the autoactivator, which reduces its DNA-binding functions and rende...
متن کاملinhibition of quorum sensing-controlled virulence factor production in pseudomonas aeruginosa by quercus infectoria gall extracts
background and objectives: this study was designed to evaluate the activity of quercus infectoria galls extract (qifge) on virulence factor production and inhibition of quorum sensing (qs) in pseudomonas aeruginosa. materials and methods: minimum inhibitory concentration (mic) of qifge against 5 strains of p. aeruginosa was determined. the extract at sub-mic was used to determine biofilm format...
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ژورنال
عنوان ژورنال: Molecular Plant Pathology
سال: 2012
ISSN: 1464-6722
DOI: 10.1111/mpp.12003